Author

David Li

MRC Laboratory of Molecular BiologyPrimary ORCID profile (0000-0002-8921-5168 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

David LiiD2 papers · Arc Research Institute

Biology Disciplines

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Physiology· 2 Biophysics· 1

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Research Focus:cell type annotation· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Rebecca G. WellsiD· 2 shared Abigail E. LonekeriD· 1 shared Chang JiangiD· 1 shared Christopher J. ChangiD· 1 shared Dominic SantoleriiD· 1 shared Donita C. BradyiD· 1 shared Elaine M. MihelciD· 1 shared Feroza K. ChoudhuryiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPhysiology

Rebecca G. WellsORCID

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Author profile →

3 papers

Recent·Most cited

Reduction in Hepatic Phosphatidylcholine Biosynthesis Promotes MASH Through Copper Deficiency

Jaclyn E. Welles, James P. Garifallou, Michael V. Gonzalez, Dominic Santoleri, Feroza K. Choudhury, Gina M. DeNicola, Ryan W. Martin, Chang Jiang, Jaehee Kim, Gen Li, Yuichi Aki, Christopher J. Chang, David Li, Rebecca G. Wells, Yang Xiao, , Paul M. Titchenell

This study shows that reduced hepatic phosphatidylcholine biosynthesis leads to copper deficiency, which promotes MASH through disrupted copper distribution and fibrogenesis.

bioRxiv · May 14, 2026 · PreprintPhysiology

Cryo-EM image processing of amyloid filaments in RELION-5.1

Sofia Lövestam, Jenny Shi, David Li, Kiarash Jamali, Sjors H. W. Scheres

The paper introduces new tools in RELION-5.1 for automated processing and analysis of cryo-EM images of amyloid filaments, demonstrating their application on experimental datasets.

bioRxiv · Mar 17, 2026 · PreprintBiophysics

Intrahepatic crystals from elevated dietary cholesterol are sufficient to stiffen the liver

David Li, Abigail E. Loneker, Yasmine Safraou, Jamie Ford, Elaine M. Mihelc, Sadatsugu Sakane, Tatiana Kisseleva, Kandice R. Levental, Ilya Levental, Ingolf Sack, Paul A. Janmey, Rebecca G. Wells

This study shows that elevated dietary cholesterol in rats leads to liver lipid crystals, which increase tissue stiffness and fibrosis progression in a model of MASLD.

Proceedings of the National Academy of Sciences · Jan 7, 2026Peer-reviewedPhysiology