Lipid metabolism of hepatocyte-like cells supports intestinal tumor growth in Drosophila
Kerui Huang, Ting Miao, Y. Chen, E Dantas, J. Sanford, John M. Asara, SJ. Moon, Yanhui Hu, K. Wang, M. Han, Marcus DaSilva Goncalves, Norbert Perrimon
The paper shows that lipid metabolism in Drosophila hepatocyte-like cells supports intestinal tumor growth through the TORC1-Hnf4 pathway, with potential therapeutic implications for cancer-associated metabolic dysfunction.
Nature Communications · Jul 3, 2026Peer-reviewedCell Biology