Lipid metabolism of hepatocyte-like cells supports intestinal tumor growth in Drosophila
Kerui Huang, Ting Miao, Y. Chen…·Norbert Perrimon
The paper shows that lipid metabolism in Drosophila hepatocyte-like cells supports intestinal tumor growth through the TORC1-Hnf4 pathway, with potential therapeutic implications for cancer-associated metabolic dysfunction.