Author

E. A. Farkash

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

A. H. Sawalha· 1 shared A. Sawalha· 1 shared B. Kaur· 1 shared B. Miglioranza Scavuzzi· 1 shared D. M. Rohraff· 1 shared F. Benavides· 1 shared F. W. Miller· 1 shared J. Callahan Fox· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. H. Sawalha

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2 papers

Recent·Most cited

The lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope

B. Miglioranza Scavuzzi, V. van Drongelen, B. Kaur, J. Callahan Fox, J. Liu, R. A. Mesquita-Ferrari, J. M. Kahlenberg, E. A. Farkash, F. Benavides, F. W. Miller, A. Sawalha, J. Holoshitz

This study identifies a DRB1*03:01-encoded epitope that drives a lupus-like transcriptome and cellular aberrations in macrophages, revealing a noncanonical mechanism of HLA-disease association in SLE.

bioRxiv · May 31, 2022 · PreprintImmunology

Inhibition of EZH2 ameliorates lupus-like disease in MRL/lpr mice

D. M. Rohraff, Y. He, E. A. Farkash, M. Schonfeld, P.-S. Tsou, A. H. Sawalha

This study shows that inhibiting EZH2 reduces lupus-like disease in MRL/lpr mice by improving survival and decreasing anti-dsDNA antibodies and inflammation.

bioRxiv · Dec 25, 2018Immunology