Author

B. Kaur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 1 Immunology· 1 Pathology· 1 Pharmacology & Toxicology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2

Frequent Co-Authors

C. Sokota· 2 shared D. P. Ennis· 2 shared G. Giannone· 2 shared J. Krell· 2 shared J. McDermott· 2 shared N. Singh· 2 shared Z. Cheng· 2 shared A. Batushansky· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

C. Sokota

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Author profile →

8 papers

Recent·Most cited

Synovial fluid transcriptome dynamics in osteoarthritis progression: Implications in pathogenesis

R. Sharma, D. Rana, R. Kumar, S. Narula, A. Chaudhary, B. Kaur, K. Kaur, M. S. Dhillon, D. Chouhan, U. C. Saini, S. Sharma, J. Kaur, I. Verma

This study identifies gene expression changes and pathways involved in osteoarthritis progression using synovial fluid transcriptomes from different OA grades.

bioRxiv · Jun 24, 2024 · PreprintPathology

The genomic trajectory of ovarian high grade serous carcinoma is determined in STIC lesions

Z. Cheng, D. P. Ennis, B. Lu, H. B. Mirza, C. Sokota, B. Kaur, N. Singh, O. Le Saux, G. Russo, G. Giannone, L. A. Tookman, J. Krell, J. McDermott, C. Barnes, I. A. McNeish

This study shows that high ploidy and whole genome duplication in ovarian high-grade serous carcinoma originate in STIC lesions, indicating early determination of the tumor's genomic trajectory.

bioRxiv · Mar 11, 2024 · PreprintCancer Biology

Curcumin alleviates Arsenic trioxide-induced behavioural impairment, oxidative damage & morphological alterations in striatal region of mice brain

K. K. Pandey, K. Mehta, B. Kaur, P. Dhar, S. Kaler

This study shows curcumin reduces arsenic trioxide-induced behavioral, oxidative, and morphological damage in mice striatal regions.

bioRxiv · Dec 14, 2023 · PreprintPharmacology & Toxicology

The lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope

B. Miglioranza Scavuzzi, V. van Drongelen, B. Kaur, J. Callahan Fox, J. Liu, R. A. Mesquita-Ferrari, J. M. Kahlenberg, E. A. Farkash, F. Benavides, F. W. Miller, A. Sawalha, J. Holoshitz

This study identifies a DRB1*03:01-encoded epitope that drives a lupus-like transcriptome and cellular aberrations in macrophages, revealing a noncanonical mechanism of HLA-disease association in SLE.

bioRxiv · May 31, 2022 · PreprintImmunology

Modeling of Aryl Hydrocarbon Receptor Pathway Intrinsic Immunometabolic Role using Glioblastoma Stem Cells and Patient-Derived Organoids

F. Watanabe, E. W. Hollingsworth, Y. Banasavadi-Siddegowda, J. M. Bartley, S. T. Sizemore, L. Yu, M. Pietrzak, P. Schiapparelli, V. Puduvalli, B. Kaur, A. Quinones-Hinojosa, J. Imitola

This study identifies AHR's role in regulating intrinsic immunity, proliferation, and migration in GBM stem cells and organoids, linking it to poor prognosis and suggesting it as a therapeutic target.

bioRxiv · Mar 17, 2022 · PreprintCancer Biology

Homogeneity of antibody-drug conjugates critically impacts the therapeutic efficacy in brain tumors

Y. Anami, Y. Otani, W. Xiong, S. Y. Y. Ha, A. Yamaguchi, N. Zhang, Z. An, B. Kaur, K. Tsuchikama

This study shows that homogeneous antibody-drug conjugates (ADCs) improve therapeutic efficacy in glioblastoma models compared to heterogeneous ADCs.

bioRxiv · Dec 23, 2021Bioengineering

The genomic landscape of early stage ovarian high grade serous carcinoma

Z. Cheng, H. Mirza, D. P. Ennis, P. Smith, L. Morrill, C. Sokota, G. Giannone, T. Goranova, T. Bradley, A. Piskorz, M. Lockley, The BriTROC Investigators, B. Kaur, N. Singh, L. Tookman, , I. McNeish

This study compares genomic features of early and late stage high grade serous ovarian carcinoma, finding no unique mutations or focal copy number alterations but noting differences in ploidy and copy number signatures.

bioRxiv · May 5, 2021Cancer Biology

Persistent homology demarcates a leaf morphospace

M. Li, H. An, R. Angelovici, C. Bagaza, A. Batushansky, L. Clark, V. Coneva, M. Donoghue, E. Edwards, D. Fajardo, H. Fang, M. Frank, T. Gallaher, S. Gebken, T. Hill, , D. H. Chitwood

This paper uses persistent homology to analyze leaf shapes from 182,707 leaves across 141 plant families, revealing phylogenetic and geographic differences in leaf morphology.

bioRxiv · Jun 20, 2017Plant Biology