The lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope
B. Miglioranza Scavuzzi, V. van Drongelen, B. Kaur…·J. Holoshitz
This study identifies a DRB1*03:01-encoded epitope that drives a lupus-like transcriptome and cellular aberrations in macrophages, revealing a noncanonical mechanism of HLA-disease association in SLE.