Author

E. Aston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Channon· 1 shared A. F. Lingappa· 1 shared A. J. McBain· 1 shared A. Kitaygorodskyy· 1 shared A. Mueller-Schiffmann· 1 shared A. Nalca· 1 shared B. Fabbri· 1 shared C. Ewald· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperEvolutionary Biology

A. Channon

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Author profile →

2 papers

Recent·Most cited

Small Molecule Protein Assembly Modulators with Pan-Cancer Therapeutic Efficacy

A. F. Lingappa, O. Akintunde, C. Ewald, M. Froehlich, N. Ziari, M. Michon, S. F. Yu, S. Mallesh, J. Lin, A. Kitaygorodskyy, D. Solas, J. C. Reed, J. R. Lingappa, A. Mueller-Schiffmann, C. Korth, , V. R. Lingappa

The paper identifies two small molecules with pan-cancer cytotoxicity and validates their anti-tumor effects in xenograft models, showing they target TRIM28/KAP1-containing complexes involved in cancer survival.

bioRxiv · Sep 28, 2022Cancer Biology

Opposing effects of population density and stress on Escherichia coli mutation rate

R. Krasovec, H. Richards, D. R. Gifford, R. V. Belavkin, A. Channon, E. Aston, A. J. McBain, C. G. Knight

This study shows that population density and stress have opposing effects on mutation rates in Escherichia coli, with mutation rates minimized at intermediate nutrient levels.

bioRxiv · Jan 30, 2018Evolutionary Biology