V. R. Lingappa

The paper identifies two small molecules with pan-cancer cytotoxicity and validates their anti-tumor effects in xenograft models, showing they target TRIM28/KAP1-containing complexes involved in cancer survival.

This paper identifies two small molecules that inhibit HIV-1 assembly by targeting host factors involved in Gag assembly, showing efficacy against drug-resistant strains and lacking resistance mutations in Gag.

This study shows that feline immunodeficiency virus (FIV) Gag forms assembly intermediates similar to HIV-1, involving ABCE1 and DDX6, indicating conserved viral-host interactions in lentivirus capsid assembly.