IFN-γ primes bone marrow neutrophils to acquire regulatory functions in severe viral respiratory infections
F. Creusat, Y. Jouan, L. Gonzalez, E. Barsac, G. Ilango, R. Lemoine, D. Soulard, C. Boisseau, A. Guillon, Q. Lin, C. de Amat Herbozo, V. Sencio, N. Winter, F. Trottein, M. Si-Tahar, , C. Paget
The paper identifies PD-L1+ neutrophils in severe viral respiratory infections, showing they have regulatory functions and are generated in the bone marrow via IFN-γ.
bioRxiv · Nov 23, 2023Immunology