Bona fide cytotoxic iNKT cells with superior antitumour responses identified in mice and humans
C. de Amat Herbozo, S. W. Wong, M. Kuypers, G. Ilango, Z. Liu, J. A. Matthews, A. Nguyen, A. Veillette, J. L. Gommerman, T. Baranek, S. Q. Crome, M. S. Tsao, A. G. Sacher, C. Paget, T. Mallevaey
This study identifies specific iNKT cell subsets in mice and humans with enhanced antitumor activity, suggesting potential improvements for adoptive cell therapies.
bioRxiv · Jul 18, 2024 · PreprintImmunology