Author

E. Birney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:DNA methylation· 3 Approach:statistical model· 3 Assay:ChIP-seq· 2 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Melamed· 2 shared C. R. M. Bangham· 2 shared T. W. Fitzgerald· 2 shared A. Ernst· 1 shared A. Leger· 1 shared A. Witkover· 1 shared C. Barton· 1 shared F. Schueder· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. Melamed

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Long-read sequencing of diagnosis and post-therapy medulloblastoma reveals complex rearrangement patterns and epigenetic signatures

T. Rausch, R. Snajder, A. Leger, M. Simovic, O. Stegle, E. Birney, M. J. Bonder, A. Ernst, J. O. Korbel

This study uses long-read sequencing to analyze medulloblastoma genomes and epigenomes, revealing complex structural variants and methylation patterns.

bioRxiv · Feb 20, 2022Cancer Biology

Selective clonal persistence of human retroviruses in vivo: radial chromatin organization, integration site and host transcription

A. Melamed, T. W. Fitzgerald, Y. Wang, J. Ma, E. Birney, C. R. M. Bangham

The paper identifies genomic features that determine the survival of HTLV-1 and HIV-1 clones in vivo, showing that radial chromatin organization, integration site, and host transcription influence clonal persistence.

bioRxiv · Nov 10, 2021Microbiology

Nanoscale 3D DNA tracing in single human cells visualizes loop extrusion directly in situ

K. S. Beckwith, O. Oedegaard Fougner, N. R. Morero, C. Barton, F. Schueder, W. Tang, S. Alexander, J.-M. Peters, R. Jungmann, E. Birney, J. Ellenberg

This study uses nanoscale 3D imaging to show that DNA folds as flexible coils without loop extruding enzymes, but forms reproducible loops with Cohesin and CTCF.

bioRxiv · Apr 12, 2021 · PreprintCell Biology

The human leukemia virus HTLV-1 alters the structure and transcription of host chromatin in cis

A. Melamed, H. Yaguchi, M. Miura, A. Witkover, T. W. Fitzgerald, E. Birney, C. R. M. Bangham

This study shows HTLV-1 disrupts host chromatin structure and causes abnormal transcription patterns in cis.

bioRxiv · Mar 7, 2018Microbiology