Cell BiologybioRxiv
Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability
G. Unlu, B. Prizer, R. Erdal…·K. Birsoy
The paper identifies SLCO2B1 as a heme transporter that enhances cellular iron availability under iron restriction, bypassing transferrin receptor-mediated uptake.
DOI 10.1016/j.molcel.2022.05.024