Author

H.-W. Yeh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

G. Unlu· 2 shared H. Ai· 2 shared K. Birsoy· 2 shared B. Allwein· 1 shared B. Prizer· 1 shared C. Xing· 1 shared E. C. Bayraktar· 1 shared E. R. Gamazon· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

G. Unlu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BiochemistrybioRxivPreprintApr 13, 2023

Development, Characterization, and Structural Analysis of a Genetically Encoded Red Fluorescent Peroxynitrite Biosensor

Y. Pang, M. Huang, Y. Fan…·H. Ai

The paper develops a red fluorescent peroxynitrite biosensor (pnRFP) using a genetically encoded boronic acid-containing amino acid, characterizes its properties, and elucidates its sensing mechanism through structural analysis.

DOI 10.1101/2023.04.13.536636

fluorescence / live-cell microscopyexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivFeb 6, 2022

Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability

G. Unlu, B. Prizer, R. Erdal…·K. Birsoy

The paper identifies SLCO2B1 as a heme transporter that enhances cellular iron availability under iron restriction, bypassing transferrin receptor-mediated uptake.

DOI 10.1016/j.molcel.2022.05.024

humangenetic perturbation / CRISPR

𝕏 PostBluesky

BiochemistrybioRxivSep 15, 2021

SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells

Y. Wang, F. S. Yen, X. G. Zhu…·K. Birsoy

This study identifies SLC25A39 as a mitochondrial glutathione importer and shows its role in cell proliferation and red blood cell development, with GSH availability regulating its abundance.

DOI 10.1038/s41586-021-04025-w

mousehuman

𝕏 PostBluesky

BiochemistrybioRxivJan 22, 2019

Identification of Factors Complicating Bioluminescence Imaging

H.-W. Yeh, T. Wu, M. Chen, H. Ai

This study identifies factors affecting bioluminescence imaging results, such as ATP dependency and serum stability, to improve data interpretation.

DOI 10.1021/acs.biochem.8b01303

imagingexperimental assay

𝕏 PostBluesky