Author

G. Unlu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

H.-W. Yeh· 2 shared K. Birsoy· 2 shared B. Allwein· 1 shared B. Prizer· 1 shared C. Xing· 1 shared E. C. Bayraktar· 1 shared E. R. Gamazon· 1 shared F. S. Yen· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

H.-W. Yeh

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2 papers

Recent·Most cited

Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability

G. Unlu, B. Prizer, R. Erdal, H.-W. Yeh, E. C. Bayraktar, K. Birsoy

The paper identifies SLCO2B1 as a heme transporter that enhances cellular iron availability under iron restriction, bypassing transferrin receptor-mediated uptake.

bioRxiv · Feb 6, 2022Cell Biology

SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells

Y. Wang, F. S. Yen, X. G. Zhu, R. C. Timson, R. Weber, C. Xing, Y. Liu, B. Allwein, H. Luo, H.-W. Yeh, S. Heissel, G. Unlu, E. R. Gamazon, M. G. Kharas, R. Hite, K. Birsoy

This study identifies SLC25A39 as a mitochondrial glutathione importer and shows its role in cell proliferation and red blood cell development, with GSH availability regulating its abundance.

bioRxiv · Sep 15, 2021Biochemistry