BiochemistrybioRxiv
Gut Microbial Trimethylamine is Elevated in Alcohol-Associated Hepatitis and Contributes to Ethanol-Induced Liver Injury in Mice
R. N. Helsley, T. Miyata, A. Kadam…·J. M. Brown
This study shows elevated trimethylamine (TMA) in alcohol-associated hepatitis patients and demonstrates that inhibiting gut microbial TMA production protects mice from ethanol-induced liver injury.
DOI 10.7554/elife.76554