Author

A. Kadam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:E. coli· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:ecology & biodiversity· 1 Organism:human· 1

Frequent Co-Authors

J. M. Brown· 2 shared L. J. Osborn· 2 shared A. Bellar· 1 shared A. Cooper· 1 shared A. Hinton· 1 shared A. J. McCullough· 1 shared A. Kim· 1 shared A. Kinder· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

J. M. Brown

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Author profile →

4 papers

Recent·Most cited

3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights into MFN-2 Mediated Changes

E. Scudese, Z. Vue, P. Katti, A. Marshall, M. Demirci, L. Vang, E. Garza Lopez, K. Neikirk, H. Le, D. Stephens, D. D. Hall, R. Rostami, T. Rodman, K. Kabugi, J.-q. Shao, , A. Hinton

This study investigates age-related changes in mitochondrial 3D structure in human skeletal muscle and shows that exercise can restore mitochondrial integrity through mitofusin 2.

bioRxiv · Nov 13, 2023Biophysics

The effect of migration and variation on populations of Escherichia coli adapting to complex fluctuating environments

S. Selveshwari, K. C. Khaire, A. Kadam, S. Dey

This study shows that migration can reduce fitness in fluctuating environments, but variation in immigrants can mitigate this effect.

bioRxiv · Mar 22, 2022Evolutionary Biology

Gut Microbial Trimethylamine is Elevated in Alcohol-Associated Hepatitis and Contributes to Ethanol-Induced Liver Injury in Mice

R. N. Helsley, T. Miyata, A. Kadam, V. Venkateshwari, N. Sangwan, E. C. Huang, R. Banerjee, A. L. Brown, K. K. Fung, W. Massey, C. Neumann, O. Danny, L. J. Osborn, R. C. Schugar, M. R. McMullen, , J. M. Brown

This study shows elevated trimethylamine (TMA) in alcohol-associated hepatitis patients and demonstrates that inhibiting gut microbial TMA production protects mice from ethanol-induced liver injury.

bioRxiv · Dec 31, 2021Biochemistry

Identification of essential genes for Escherichia coli aryl polyene biosynthesis and function in biofilm formation

I. Johnston, L. J. Osborn, R. L. Markley, E. A. McManus, A. Kadam, K. B. Schultz, N. Nagajothi, P. A. Ahern, J. M. Brown, J. Claesen

This study identifies essential genes for aryl polyene biosynthesis in E. coli and shows APEs enhance biofilm formation and oxidative stress resistance.

npj Biofilms and Microbiomes · Jul 2, 2021Peer-reviewedMicrobiology