A prostate cancer gastrointestinal transcriptional phenotype may be associated with diminished response to AR-targeted therapy
A. Subramanian, M. Zhang, M. Sharifi, T. Moreno-Rodriguez, E. Feng, N. R. Rydzewski, R. Shrestha, X. Zhu, S. G. Zhao, R. Aggarwal, E. J. Small, C.-K. C. Ding, D. A. Quigley, M. Sjöström
This study identifies a gastrointestinal gene expression phenotype in metastatic castration-resistant prostate cancer that correlates with reduced response to androgen receptor inhibitors.
bioRxiv · Jun 2, 2024 · PreprintCancer Biology