C. Sharma

Phosphoketolase and KDPG aldolase metabolism modulate photosynthetic carbon yield in cyanobacteria

This study shows that phosphoketolase and KDPG aldolase metabolism in cyanobacteria modulate photosynthetic carbon yield by optimizing carbon resource allocation during dark respiration.

MtbEis protein: A new player in stringent response of Mycobacterium tuberculosis

This study identifies MtbEis as an acetyltransferase that enhances RelMtb's pppGpp synthesis, improving M. tuberculosis survival under starvation conditions.

Inferring Spatially Resolved Transcriptomics Data from Whole Slide Images for the Assessment of Colorectal Tumor Metastasis: A Feasibility Study

This study investigates using deep learning to predict spatial transcriptomics data from whole slide images to assess colorectal tumor metastasis, finding that convolutional networks outperform transformer and graph-based models.

Graph neural networks ameliorate potential impacts of imprecise large-scale autonomous immunofluorescence labeling of immune cells on whole slide images

This study uses graph neural networks to improve TIL classification on whole slide images by leveraging contextual features from immunofluorescence labeling.

Host cholesterol dependent activation of VapC12 toxin enriches persister population during Mycobacterium tuberculosis infection

This study identifies cholesterol-dependent activation of the VapC12 toxin in Mycobacterium tuberculosis as a mechanism that increases persister formation during infection.