Potential to Enhance Large Scale Molecular Assessments of Skin Photoaging through Virtual Inference of Spatial Transcriptomics from Routine Staining
G. Srinivasan, M. Davis, M. LeBoeuf, M. Fatemi, Z. Azher, Y. Lu, A. Diallo, M. Montivero, F. Kolling, L. Perrard, L. Salas, B. Christensen, S. Palisoul, G. Tsongalis, L. Vaickus, , J. Levy
This paper develops machine learning models to infer spatial transcriptomics data from H&E-stained skin slides, improving the assessment of photoaging and its therapeutic implications.
bioRxiv · Jul 30, 2023 · PreprintPathology