Author

E. Freund

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Heidersbach· 1 shared A. Lun· 1 shared A. Murthy· 1 shared A. Nissenbaum· 1 shared A.-H. Capietto· 1 shared A.-J. Tong· 1 shared B. Haley· 1 shared B. L. Yaspan· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Heidersbach

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Systematic perturbation screens decode regulators of inflammatory macrophage states and identify a role for TNF mRNA m6A modification

S. M. Haag, S. Xie, C. Eidenschenk, J.-P. Fortin, M. Callow, M. Costa, A. Lun, C. Cox, S. Z. Wu, R. N. Pradhan, J. Lock, J. A. Kuhn, L. Holokai, M. Thai, E. Freund, , A. Murthy

The paper identifies regulators of inflammatory macrophage states and shows that TNF mRNA m6A modification controls its stability and contributes to disease.

bioRxiv · Apr 12, 2024 · PreprintImmunology

HLApollo: A superior transformer model for pan-allelic peptide-MHC-I presentation prediction, with diverse negative coverage, deconvolution and protein language features.

W. J. Thrift, N. W. Lounsbury, Q. Broadwell, A. Heidersbach, E. Freund, Q. Phung, Y. Abdolazimi, J. Chen, A.-H. Capietto, A.-J. Tong, C. M. Rose, C. Blanchette, J. Lill, B. Haley, L. Delamarre, , S. Jhunjhunwala

HLApollo improves MHC-I peptide presentation prediction with a transformer model, showing better performance than existing methods and offering pan-allelic generalization.

bioRxiv · Dec 8, 2022 · PreprintImmunology