Author

A. Heidersbach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

B. Haley· 2 shared A. Ashkenazi· 1 shared A. Gogineni· 1 shared A. Le Thomas· 1 shared A.-H. Capietto· 1 shared A.-J. Tong· 1 shared C. Blanchette· 1 shared C. M. Rose· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

B. Haley

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Author profile →

2 papers

Recent·Most cited

HLApollo: A superior transformer model for pan-allelic peptide-MHC-I presentation prediction, with diverse negative coverage, deconvolution and protein language features.

W. J. Thrift, N. W. Lounsbury, Q. Broadwell, A. Heidersbach, E. Freund, Q. Phung, Y. Abdolazimi, J. Chen, A.-H. Capietto, A.-J. Tong, C. M. Rose, C. Blanchette, J. Lill, B. Haley, L. Delamarre, , S. Jhunjhunwala

HLApollo improves MHC-I peptide presentation prediction with a transformer model, showing better performance than existing methods and offering pan-allelic generalization.

bioRxiv · Dec 8, 2022 · PreprintImmunology

Disruption of IRE1α through its Kinase Domain Attenuates Multiple Myeloma

J. M. Harnoss, A. Le Thomas, S. A. Marsters, D. A. Lawrence, M. Lu, Y.-C. A. Chen, J. Qing, K. Totpal, D. Kan, E. Segal, H. Ackerly Wallweber, W. Wang, K. Clark, S. Kaufman, M. Beresini, , A. Ashkenazi

This study shows that disrupting IRE1α's kinase domain reduces multiple myeloma tumor growth and enhances treatment efficacy, suggesting it as a therapeutic target.

bioRxiv · Dec 14, 2018 · PreprintCancer Biology