PhysiologybioRxivPreprint
Endogenous GDF15 and FGF21 additively alleviate hepatic steatosis and insulin resistance in obese mice.
S. Patel, A. Haider, A. Alvarez-Guaita…·D. B. Savage
This study shows that GDF15 and FGF21, secreted by the liver in obese mice, reduce hepatic steatosis and insulin resistance when both are active.
DOI 10.1101/2022.06.08.495255