Author

E. Hitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:plant (other)· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

T. S. Voss· 3 shared A. Passecker· 2 shared N. M. B. Brancucci· 2 shared A. Gomez-Mejia· 1 shared A. S. Zinkernagel· 1 shared B. T. Thommen· 1 shared C. Acevedo· 1 shared C. Doerig· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersMicrobiology

T. S. Voss

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Revisiting the effect of pharmaceuticals on transmission stage formation in the malaria parasite Plasmodium falciparum

B. T. Thommen, A. Passecker, T. Buser, E. Hitz, T. S. Voss, N. M. B. Brancucci

This study investigates how antimalarial drugs affect gametocyte formation in Plasmodium falciparum, finding that drug-induced effects on sexual commitment are only observed at concentrations that inhibit parasite survival.

bioRxiv · Nov 18, 2021Cell Biology

The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites

E. Hitz, N. Wiedemar, A. Passecker, N. M. B. Brancucci, I. Vakonakis, P. Maeser, T. S. Voss

This study identifies PfPDK1 as an essential upstream activator of PfPKAc in malaria parasites, crucial for parasite survival and a potential drug target.

bioRxiv · May 27, 2021Microbiology

Blunted Fas signaling favors RIPK1-driven neutrophil necroptosis in critically ill COVID-19 patients

T. A. Schweizer, S. Mairpady Shambat, C. Vulin, S. Hoeller, C. Acevedo, M. Huemer, A. Gomez-Mejia, C.-C. Chang, J. Baum, S. Hertegonne, E. Hitz, D. A. Hofmaenner, P. K. Buehler, H. Moch, R. A. Schuepbach, , A. S. Zinkernagel

The paper shows that in critically ill COVID-19 patients, dysregulated Fas signaling leads to increased RIPK1-driven necroptosis in neutrophils, contributing to disease severity.

bioRxiv · Mar 19, 2021 · PreprintImmunology

GDV1 C-terminal truncation of 39 amino acids disrupts sexual commitment in Plasmodium falciparum

M. Tiburcio, E. Hitz, I. Niederwieser, G. Kelly, H. Davies, C. Doerig, O. Billker, T. S. Voss, M. Treeck

This study identifies a C-terminal truncation mutation in GDV1 that disrupts sexual commitment in Plasmodium falciparum by destabilizing the protein, despite normal nuclear import and HP1 interaction.

bioRxiv · Oct 28, 2020Microbiology