T. S. Voss

This study measures sexual commitment rates in Plasmodium falciparum using two methods, finds higher sensitivity with an early marker, and reports variation across isolates and lab lines.

This study investigates how antimalarial drugs affect gametocyte formation in Plasmodium falciparum, finding that drug-induced effects on sexual commitment are only observed at concentrations that inhibit parasite survival.

This study identifies PfPDK1 as an essential upstream activator of PfPKAc in malaria parasites, crucial for parasite survival and a potential drug target.

This study investigates PfHP1 domains in Plasmodium falciparum using CRISPR/Cas9 and DiCre/LoxP, showing their roles in nuclear targeting, heterochromatin formation, and parasite proliferation.

The paper identifies PfAP2-HC as a heterochromatin component in Plasmodium falciparum, showing it binds heterochromatin without DNA-binding and is dependent on heterochromatin protein 1.

This study identifies a C-terminal truncation mutation in GDV1 that disrupts sexual commitment in Plasmodium falciparum by destabilizing the protein, despite normal nuclear import and HP1 interaction.

This paper develops CRISPR/Cas9-engineered inducible gametocyte producer lines for mass production of P. falciparum gametocytes, achieving 75% sexual commitment and enabling genetic studies of transmission stages.

This study uses complexome profiling to analyze mitochondrial protein complexes in Plasmodium falciparum across different life stages, revealing stage-specific composition and functional shifts.