Author

E. J. Shpall

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

D. Mak· 2 shared D. Marin· 2 shared E. Ensley· 2 shared E. Gokdemir· 2 shared H. Shaim· 2 shared J. Wang· 2 shared K. Chen· 2 shared K. Rezvani· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

D. Mak

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cancer BiologybioRxivDec 10, 2021

3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib

I. M. Meraz, M. Majidi, B. Fang…·J. A. Roth

This study identifies PDK1 as a driver of osimertinib resistance in NSCLC, showing its inhibition sensitizes resistant cells and correlates with disease progression.

DOI 10.1038/s42003-023-04889-w

humanbulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivSep 18, 2021

Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment

Z. Schwabkey, D. Wiesnoski, C.-C. Chang…·E. J. Shpall

The paper links diet-derived metabolites and mucus to fever after cytotoxic cancer treatment by showing how Akkermansia muciniphila affects colonic mucus and inflammation.

DOI 10.1126/scitranslmed.abo3445

mousehuman

𝕏 PostBluesky

ImmunologybioRxivSep 15, 2020

Generation of glucocorticoid resistant SARS-CoV-2 T-cells for adoptive cell therapy

R. Basar, N. Uprety, E. Ensley…·K. Rezvani

The paper expands SARS-CoV-2 T-cells from COVID-19 donors using IL-2/4/7 cytokines, achieving >1000-fold expansion with preserved function, and inactivates the glucocorticoid receptor to create glucocorticoid-resistant T-cells for adoptive therapy.

DOI 10.1016/j.celrep.2021.109432

humanflow cytometry

𝕏 PostBluesky

ImmunologybioRxivPreprintMar 29, 2020

CIS checkpoint deletion enhances the fitness of cord blood derived natural killer cells transduced with a chimeric antigen receptor

K. Rezvani, M. Daher, R. Basar…·Wei Inn

This paper combines CIS checkpoint deletion with CAR engineering in NK cells to enhance their metabolic fitness and anti-tumor activity in a lymphoma model.

DOI 10.1101/2020.03.29.014472

mouseproteomics

𝕏 PostBluesky