Inhibition of CD226 Co-Stimulation Suppresses Diabetes Development in the NOD Mouse by Augmenting Tregs and Diminishing Effector T Cell Function
M. Brown, P. Thirawatananond, L. Peters, E. Kern, S. Vijay, L. Sachs, A. L. Posgai, M. Brusko, M. Shapiro, C. E. Mathews, R. E. Bacher, T. Brusko
This study shows that blocking CD226 reduces diabetes in NOD mice by enhancing Treg function and reducing effector T cell activity.
bioRxiv · Jul 16, 2024 · PreprintImmunology