Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
M. R. Shapiro, X. Dong, D. Perry, J. M. McNichols, P. Thirawatananond, A. L. Posgai, L. Peters, K. Motwani, R. Musca, A. Muir, P. Concannon, L. Jacobsen, C. E. Mathews, C. H. Wasserfall, M. J. Haller, , T. M. Brusko
The paper uses flow cytometry to show accelerated immune aging and age-adjusted proinflammatory phenotypes in type 1 diabetes.
JCI Insight · Sep 8, 2023Peer-reviewedImmunology
K. R. Sylvester-Armstrong, C. F. Reeder, A. Powell, M. W. Becker, D. W. Hagan, J. Chen, C. E. Mathews, C. H. Wasserfall, M. A. Atkinson, R. Egerman, E. A. Phelps
This study shows that serum from pregnant donors can stimulate human beta cell proliferation and insulin secretion, suggesting potential for beta cell expansion.
bioRxiv · Apr 17, 2023 · PreprintCell Biology
L. H. Armitage, S. E. Stimpson, K. E. Santostefano, L. Sui, S. O. Ogundare, B. N. Newby, R. Castro-Gutierrez, M. K. Huber, J. P. Taylor, P. Sharma, I. Radichev, D. J. Perry, N. Fredette, A. Savinov, N. Terada, , C. E. Mathews
This paper demonstrates the use of induced pluripotent stem cells to create an isogenic system for studying genetic influences on cell-cell interactions in type 1 diabetes.
bioRxiv · May 3, 2021Immunology
L. H. Armitage, M. Khosravi Maharlooei, A. M. Meacham, E. J. Butfiloski, R. M. Viola, D. Egli, M. Sykes, M. A. Wallet, C. E. Mathews
This paper describes a highly efficient method to differentiate iPSC into monocytes, MDMs, and moDCs with high purity and yield, overcoming previous limitations in culture efficiency and scalability.
bioRxiv · Apr 29, 2021 · PreprintImmunology
J. Chen, C. Liu, A. Chernatynskaya, B. N. Newby, T. M. Brusko, X. Xu, N. Morgan, C. P. Santarlas, W. H. Reeves, H. M. Tse, J. W. Leiding, C. E. Mathews
This study shows that NOX2-derived reactive oxygen species are essential for CD8+ T cell effector function by promoting T-bet expression and mTOR complex 1 activation.
bioRxiv · Feb 24, 2021Immunology
S. E. Stimpson, J. Chen, B. N. Newby, R. Khattri, H. D. Chapman, T. E. Angelini, M. E. Merritt, D. V. Serreze, C. E. Mathews
This study shows glycolysis is essential for CD8+ T-cell effector function, while mitochondrial respiration is not, and inhibiting glycolysis reduces autoimmunity in a diabetes model.
bioRxiv · Feb 5, 2020 · PreprintImmunology