Author

H. Celik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J. Fowles· 2 shared M. Allen· 2 shared A. B. A. Laranjeira· 1 shared A. Lund Da Costa· 1 shared A. T. Ting· 1 shared A. Yildirim· 1 shared A. Z. Wang· 1 shared B. Bansal· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCancer Biology

J. Fowles

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

DUSP6 mediates resistance to JAK2 inhibition and drives leukemic progression

T. Kong, A. B. A. Laranjeira, K. Yang, D. Fisher, L. Yu, A. Z. Wang, M. Ruzinova, J. Fowles, M. Allen, H. Celik, G. Challen, S. Huang, S. Oh

This study identifies DUSP6 as a driver of leukemic progression and resistance to JAK2 inhibition in MPNs, highlighting the DUSP6-RSK1 axis as a therapeutic target.

Nature Cancer · Dec 29, 2022Peer-reviewedCancer Biology

Reliability metrics of outcome measures during the single and double leg drop jump tests

H. Celik, A. Yildirim, E. Unver, C. Mavili, E. Yilmaz, F. Ozturk, P. Arpinar-Avsar, S. A. Cinemre

This study assesses the reliability of outcome measures in single and double leg drop jump tests for collegiate athletes, finding high reliability for key metrics in both tests.

bioRxiv · Jul 10, 2022 · PreprintPhysiology

TFAM-dependent mitochondrial integrity in regulatory T cells preserves immune landscape and restrains inflammaging

K. Guo, Z. Wang, J. S. Gill, T. Debnath, B. Bansal, R. Poojary, J. K. Correa, H. Celik, H. Mehta, E. Abrham, Z. Even, M. Rahman, A. Lund Da Costa, S. Jain, X. Wang, , R. Mathur

This study identifies TFAM-dependent mitochondrial integrity in Tregs as critical for preserving immune homeostasis and preventing inflammaging.

bioRxiv · Mar 8, 2022 · PreprintImmunology

A Humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms

H. Celik, E. Krug, C. R. Zhang, W. Han, N. Issa, W. K. Koh, H. Bjeije, O. Kukhar, M. Allen, T. Li, D. A. Fisher, J. Fowles, T. N. Wong, M. C. Stubbs, H. K. Koblish, , G. A. Challen

This paper introduces a humanized animal model using patient-derived xenografts to study myeloproliferative neoplasms and identify therapeutic vulnerabilities.

bioRxiv · Nov 12, 2020Cancer Biology