Author

E. L. Lim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Mungall· 1 shared A. S. Gamis· 1 shared A. Tanaka· 1 shared B. Salhia· 1 shared C. Klein· 1 shared C. M. Zwaan· 1 shared C. Schlack-Leigers· 1 shared C. Wolf· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. Mungall

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Author profile →

3 papers

Recent·Most cited

The TCRs of pathogenic Th17 cells in arthritogenic mice are shifted toward a Treg-like repertoire

M. A. Llamas-Covarrubias, A. Tanaka, M. d. J. Loza Lopez, D. Diez, Z. Xu, E. L. Lim, S. Teraguchi, S. Sakaguchi, D. M. Standley

The paper shows that ZAP-70 mutations in mice lead to a shift in T cell repertoires, with pathogenic Th17 cells resembling Tregs and contributing to autoimmune arthritis.

bioRxiv · Mar 1, 2024 · PreprintImmunology

Endosome dysfunction leads to gain-of-function TLR7 and human lupus

H. Mishra, C. Schlack-Leigers, E. L. Lim, O. Thieck, T. Magg, J. Raedler, C. Wolf, C. Klein, H. Ewers, M. A. Lee-Kirsch, D. Meierhofer, F. Hauck, O. Majer

This study shows that endosome dysfunction causes TLR7 gain-of-function and contributes to human lupus by disrupting TLR7 turnover and leading to self-reactivity.

bioRxiv · Apr 3, 2023 · PreprintImmunology

Comprehensive characterization of pediatric AML reveals diverse fusion oncoproteins and age-specific mutational interactions

H. Bolouri, J. E. Farrar, T. J. Triche, R. E. Ries, E. L. Lim, T. A. Alonzo, Y. Ma, R. Moore, A. Mungall, M. A. Marra, J. Zhang, X. Ma, Y. Liu, Y. Liu, J. M. Guidry Auvil, , S. Meshinchi

This study characterizes the molecular landscape of pediatric AML, identifying age-specific mutations and fusion oncoproteins that differ from adult AML.

bioRxiv · Oct 10, 2017Cancer Biology