Author

M. A. Lee-Kirsch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. A. Hyman· 1 shared A. Chhabra· 1 shared A. Rapp· 1 shared C. Klein· 1 shared C. Schlack-Leigers· 1 shared C. Wolf· 1 shared D. Kuster· 1 shared D. Meierhofer· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. A. Hyman

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintApr 3, 2023

Endosome dysfunction leads to gain-of-function TLR7 and human lupus

H. Mishra, C. Schlack-Leigers, E. L. Lim…·O. Majer

This study shows that endosome dysfunction causes TLR7 gain-of-function and contributes to human lupus by disrupting TLR7 turnover and leading to self-reactivity.

DOI 10.1101/2023.04.03.535356

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivJul 12, 2022

SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA

S. Maharana, S. Kretschmer, S. Hunger…·M. A. Lee-Kirsch

This study shows SAMHD1 regulates innate immunity by controlling RNA condensation, preventing immune recognition of self RNA and reducing inflammation.

DOI 10.1016/j.molcel.2022.08.031

humanmetagenomics

𝕏 PostBluesky