Fc mediated pan-sarbecovirus protection after alphavirus vector vaccination
L. E. Adams, S. R. Leist, K. H. Dinnon, A. West, K. L. Gully, E. Anderson, J. F. Loome, E. Madden, J. Powers, A. Schaefer, S. Sarkar, I. Castillo, J. Maron, R. P. McNamara, H. L. Bertera, , R. S. Baric
This study shows that non-neutralizing antibodies targeting FcR4 and spike S2 provide cross-protection against sarbecoviruses after alphavirus vector vaccination.
bioRxiv · Nov 28, 2022Microbiology