Author

E. Mereu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 7 Approach:statistical model· 6 Research Focus:differential expression· 5 Organism:human· 5 Assay:scRNA-seq· 5 Research Focus:cell-cell communication· 4 Approach:deep learning· 3 Approach:experimental assay· 3

Frequent Co-Authors

H. Heyn· 5 shared M. Esteller· 4 shared D. Marchese· 3 shared J. L. Trincado· 2 shared M. Casado-Pelaez· 2 shared S. Ruiz· 2 shared A. Bataller· 1 shared A. Bigas· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersImmunology

H. Heyn

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Discovery and evaluation of novel biomarkers reveal dasatinib as a potential treatment for a specific subtype of Triple-Negative Breast Cancer

D. Ortega-Alvarez, D. Tebar-Garcia, M. Casado-Pelaez, E. Castillo-Agea, J. Balibrea-Rull, D. Olivares-Osuna, D. Perez-Parra, C. Guardia, E. Musulen, E. Vinuesa-Pitarch, E. Sanchez-Lopez, F. Postigo-Corrales, E. Ballana, A. Martinez-Cardus, M. Margeli, , V. Rodilla

This study identifies BC-markers in TNBC, links them to poor prognosis and dasatinib sensitivity, suggesting TAGLN as a predictive biomarker for targeted therapy.

bioRxiv · Jul 24, 2024 · PreprintCancer Biology

Integrative single-cell multi-omics of CD19CARpos and CARneg T cells suggest drivers of immunotherapy response in B-cell neoplasias

M. Guerrero-Murillo, A. Rill-Hinarejos, J. L. Trincado, A. Bataller, V. Ortiz-Maldonado, D. Benitez-Ribas, M. Espanol, E. A. Gonzalez, N. Martinez-Cibrian, D. Marchese, L. Martin-Martin, A. M. Garcia-Sancho, H. Heyn, M. Juan, A. Urbano-Ispizua, , P. Menendez

This study integrates single-cell multi-omics data from CAR-T cells to identify factors influencing immunotherapy response in B-cell neoplasias.

bioRxiv · Jan 23, 2024 · PreprintImmunology

Macrophage and neutrophil heterogeneity at single-cell spatial resolution in inflammatory bowel disease

A. Garrido-Trigo, A. Corraliza, M. Veny, I. Dotti, E. Melon-Ardanaz, A. Rill, H. L. Crowell, A. Corbi, V. Gudino, M. Esteller, I. Alvarez-Teubel, D. Aguilar, M. C. Masamunt, E. Killingbeck, Y. Kim, , A. Salas

The paper identifies macrophage and neutrophil heterogeneity in inflammatory bowel disease using single-cell and spatial transcriptomics, revealing distinct subtypes and their potential roles in disease.

bioRxiv · Nov 28, 2022 · PreprintImmunology

IκBα controls dormancy induction in Hematopoietic stem cell development via retinoic acid

R. Thambyrajah, Z. Fadlullah, M. Proffitt, W. H. Neo, Y. Guillen, M. Casado-Pelaez, P. Herrero-Molinero, C. Brujas, N. Castelluccio, J. Gonzalez, A. Iglesias, L. Marruecos, C. Ruiz-Herguido, M. Esteller, E. Mereu, , A. Bigas

This study shows that IκBα regulates hematopoietic stem cell (HSC) dormancy by controlling retinoic acid signaling during development.

bioRxiv · Nov 17, 2022 · PreprintCell Biology

Local IL-17 orchestrates skin aging

P. Sola, E. Mereu, J. Bonjoch, M. Casado, O. Reina Garcia, E. Blanco Garcia, M. Esteller, L. DiCroce, H. Heyn, G. Solanas, S. Aznar Benitah

This study identifies IL-17 as a key driver of age-related skin inflammation and shows that blocking IL-17 signaling reduces inflammatory markers and delays aging traits in skin.

bioRxiv · Jan 31, 2022 · PreprintCell Biology

Glioblastoma cell fate is differentially regulated by the microenvironments of the tumour bulk and infiltrative margin

C. Garcia-Diaz, E. Mereu, M. P. Clements, A. Pöysti, F. Galvez-Cancino, S. P. Castillo, L. Courtot, S. Ruiz, F. Roncaroli, Y. Yuan, S. A. Quezada, H. Heyn, S. Parrinello

This study compares glioblastoma cell fate in tumour bulk and margin, finding distinct neurogenic patterns and immune environments, with margin cells showing developmental-like trajectories and iNPCs linked to interferon signalling.

bioRxiv · Jun 11, 2021 · PreprintCancer Biology

A Single-Cell Tumor Immune Atlas for Precision Oncology

P. Nieto, M. Marc Elosua-Bayes, J. L. Trincado, D. Marchese, R. Massoni-Badosa, M. Salvany, A. Henriques, E. Mereu, C. Moutinho, S. Ruiz, P. Lorden, V. Chin, D. C. Kaczorowski, C.-L. Chan, R. Gallagher, , H. Heyn

The paper creates a single-cell tumor immune atlas using data from 217 patients and 13 cancer types to improve immune cell annotation and spatial mapping for precision oncology.

bioRxiv · Oct 26, 2020Cancer Biology