On the Role of VP3-PI3P Interaction in Birnavirus Endosomal Membrane Targeting
F. A. Zanetti, I. Fernandez, E. Baquero, P. Guardado-Calvo, A. Ferrino-Iriarte, S. Dubois, E. Morel, V. Alfonso, M. O. Aguilera, E. E. Celayes, L. M. Polo, L. Suhaiman, V. V. Galassi, M. V. Chiarpotti, C. Allende, , L. R. Delgui
This paper investigates how VP3 protein of birnaviruses targets endosomal membranes via PI3P binding, revealing a two-stage mechanism critical for viral replication.
bioRxiv · Feb 20, 2024Microbiology