Cancer BiologybioRxiv
Resistance to abemaciclib is associated with increased metastatic potential and lysosomal protein deregulation in breast cancer cells
E. R. Sheidemann, D. M. Demas, C. Hou…·A. N. Shajahan-Haq
This study shows that abemaciclib resistance in breast cancer cells is linked to increased metastatic potential and lysosomal protein deregulation, with potential therapeutic implications for combining lysosomal destabilizers.