ImmunologybioRxivPreprint
Loss of Usp22 enhances histone H2B monoubiquitination and stimulates intracellular and systemic interferon immunity
N. Dietlein, X. Wang, E. Rodriguez Correa…·H.-R. Rodewald
The paper shows that loss of Usp22 increases H2Bub1 levels, leading to enhanced ISG expression and IFN immunity in mice.