Cell BiologybioRxiv
Aging-Associated Decrease in the Histone Acetyltransferase KAT6B Causes Myeloid-Biased Hematopoietic Stem Cell Differentiation
E. S. Khokhar, S. Borikar, E. Eudy…·J. Trowbridge
This study shows that aging reduces KAT6B, an epigenetic regulator, leading to myeloid-biased differentiation of hematopoietic stem cells.
DOI 10.1016/j.exphem.2020.01.014