E. Sharma

High-Throughput DNA melt measurements enable improved models of DNA folding thermodynamics

This paper introduces a high-throughput method to measure DNA melting and develops models to improve DNA folding thermodynamics predictions.

Two splice forms of OsbZIP1, a homolog of AtHY5, function to regulate skoto- and photo-morphogenesis in rice

The paper shows that two splice forms of OsbZIP1, a rice homolog of AtHY5, regulate seedling development under different light conditions.

AICAR prevents doxorubicin-induced heart failure in rats by ameliorating cardiac atrophy and improving fatty acid oxidation

This study shows AICAR prevents doxorubicin-induced heart failure in rats by improving cardiac function, mitochondrial fatty acid oxidation, and preventing myocardial atrophy.

Temperature-dependent small RNA expression depends onwild genetic backgrounds of Caenorhabditis briggsae

This study shows that temperature-dependent small RNA expression varies with genetic background in C. briggsae, with piRNAs and 22G-RNAs showing reduced expression at high temperatures in temperate strains.

Electric-field-driven microfluidics for rapid CRISPR-based diagnostics and its application to detection of SARS-CoV-2

This paper develops an electric-field-driven microfluidic system for CRISPR-based diagnostics, achieving SARS-CoV-2 detection in 30 minutes from raw sample to result.

High throughput identification of miR-145 targets in human articular chondrocytes

This study identifies miR-145 targets in human articular chondrocytes using RIP-seq and validation methods, showing it regulates genes involved in cartilage homeostasis and inflammation.