Author

E. Thai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

J.-P. Julien· 3 shared A. Bosch· 2 shared E. A. Levashina· 2 shared G. Costa· 2 shared H. Wardemann· 2 shared K. Prieto· 2 shared R. Murugan· 2 shared S. W. Scally· 2 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

J.-P. Julien

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Author profile →

3 papers

Recent·Most cited

Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11

I. Kucharska, E. Thai, A. Srivastava, J. L. Rubinstein, R. Pomes, J.-P. Julien

This study investigates how antibody 3D11 binds to Plasmodium berghei CSP repeats, inducing structural ordering and revealing common mechanisms of antibody evolution against Plasmodium CSP.

bioRxiv · Jun 2, 2020Microbiology

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity

E. Thai, G. Costa, A. Weyrich, R. Murugan, D. Oyen, K. Prieto, A. Bosch, A. Valleriani, N. C. Wu, T. Pholcharee, S. W. Scally, I. A. Wilson, H. Wardemann, J.-P. Julien, E. A. Levashina

This study characterizes a monoclonal antibody against the N-terminal domain of PfCSP, finding it has high affinity but lacks functional inhibitory activity against sporozoites.

bioRxiv · Jan 13, 2020Immunology

Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs

R. Murugan, S. W. Scally, G. Costa, G. Mustafa, E. Thai, T. Decker, A. Bosch, K. Prieto, E. A. Levashina, J.-P. Julien, H. Wardemann

The paper characterizes 200 human monoclonal PfCSP antibodies, showing that high affinity to a conserved NANP motif, not cross-reactivity, correlates with parasite inhibition and protection.

bioRxiv · Oct 9, 2019Immunology