Author

A. Bosch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

E. A. Levashina· 2 shared E. Thai· 2 shared G. Costa· 2 shared H. Wardemann· 2 shared J.-P. Julien· 2 shared K. Prieto· 2 shared R. Murugan· 2 shared S. W. Scally· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

E. A. Levashina

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Adsorption-driven deformation and landing-footprints of the RBD proteins in SARS-CoV-2 variants onto biological and inanimate surfaces

A. Bosch, H. V. Guzman, R. Perez

This study examines how RBD mutations in SARS-CoV-2 affect adsorption to hydrophobic and hydrophilic surfaces, revealing structural deformations and distinct landing-footprints.

bioRxiv · Jan 15, 2024 · PreprintBiophysics

Molecular Epidemiology of multidrug-resistant Klebsiella pneumoniae, Enterobacter cloacae, and Escherichia coli outbreak among neonates in Tembisa Hospital, South Africa

J. O. Sekyere, M. Mmatli, A. Bosch, R. V. Ntsoane, H. Naidoo, S. Doyisa, N. E. Maningi, N. M. Mbelle, M. Said

The paper investigates an outbreak of multidrug-resistant bacteria in a neonatal ward, identifying clonal and plasmid-mediated spread of resistance genes.

bioRxiv · Dec 15, 2023 · PreprintMicrobiology

Profiling cell envelope-antibiotic interactions reveals vulnerabilities to β-lactams in a multidrug-resistant bacterium

A. M. Hogan, A. Natarajan, D. T. Maydaniuk, B. Leon, Z. Batun, A. Motnenko, A. Bosch, S. T. Cardona

This study identifies cell envelope-associated resistance and susceptibility determinants in Burkholderia cenocepacia using transposon mutagenesis and antibiotic profiling, revealing new vulnerabilities to β-lactams and the mechanism of cefiderocol.

Nature Communications · Aug 9, 2023Peer-reviewedMicrobiology

Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate

E. Prieto-Fernandez, L. Egia-Mendikute, L. Vila-Vecilla, A. Bosch, A. Barreira-Manrique, S. Y. Lee, A. Garcia del Rio, A. Antonana-Vildosola, B. Jimenez-Lasheras, L. Moreno-Cugnon, J. Jimenez-Barbero, E. Berra, J. Ereno-Orbea, A. Palazon

This study shows hypoxia reduces SARS-CoV-2 spike protein attachment to epithelial cells by lowering ACE2, NRP1, and HS levels, suggesting hypoxia may limit infection.

bioRxiv · Jan 9, 2021Cell Biology

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity

E. Thai, G. Costa, A. Weyrich, R. Murugan, D. Oyen, K. Prieto, A. Bosch, A. Valleriani, N. C. Wu, T. Pholcharee, S. W. Scally, I. A. Wilson, H. Wardemann, J.-P. Julien, E. A. Levashina

This study characterizes a monoclonal antibody against the N-terminal domain of PfCSP, finding it has high affinity but lacks functional inhibitory activity against sporozoites.

bioRxiv · Jan 13, 2020Immunology

Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs

R. Murugan, S. W. Scally, G. Costa, G. Mustafa, E. Thai, T. Decker, A. Bosch, K. Prieto, E. A. Levashina, J.-P. Julien, H. Wardemann

The paper characterizes 200 human monoclonal PfCSP antibodies, showing that high affinity to a conserved NANP motif, not cross-reactivity, correlates with parasite inhibition and protection.

bioRxiv · Oct 9, 2019Immunology