E.-S. Park

Interplay of IGF1R and estrogen signaling regulates hematopoietic stem and progenitor cells

This study shows that IGF1R and estrogen signaling interact to regulate HSPC proliferation, with sex-specific effects observed in adult and fetal hematopoiesis.

Identification of inosine monophosphate dehydrogenase as a potential target for anti-monkeypox virus agents

This study identifies IMPDH as a potential target for anti-monkeypox virus agents by showing that compounds targeting this enzyme inhibit MPXV replication more effectively than existing treatments.

Human XIRP1 is a macrophage podosome protein utilized by Listeria for actin-based motility

The paper identifies XIRP1 as a macrophage podosome protein used by Listeria for actin-based motility, showing its role in host-pathogen interactions during infection.

Potential anti-monkeypox virus activity of atovaquone, mefloquine, and molnupiravir, and their potential use as treatments

This study identifies atovaquone, mefloquine, and molnupiravir as potential anti-monkeypox virus drugs, with atovaquone showing enhanced efficacy when combined with tecovirimat.

Subacute SARS-CoV-2 replication can be controlled in the absence of CD8+ T cells in cynomolgus macaques

This study shows that subacute SARS-CoV-2 replication can be controlled without CD8+ T cells in cynomolgus macaques, suggesting CD8+ T-cell dysfunction may not solely cause viral control failure.

Development of a reverse transcription polymerase chain reaction for the detection of severe fever with thrombocytopenia syndrome virus from suspected infected animals

This paper develops an RT-PCR assay to detect SFTSV in suspected animals, identifying 5 positive cases among 56 samples and demonstrating its sensitivity and specificity.