Emily Middendorp Guerra

The paper investigates how inflammation reprograms goblet cells into tumor-initiating cells in colon cancer using single-cell RNAseq and mutation spectrum analysis.

This study identifies mechanical phenotype differences between LGR5+ and LGR5- colorectal cancer cells, linking them to membrane to cortex attachment proteins and metastatic potential.

This study shows that increased simple spike activity in Purkinje cells, facilitated by long-term potentiation at parallel fiber synapses, contributes to whisker reflex adaptation in mice.