PhysiologybioRxivPreprint
Brown adipocyte NOSEMPE promotes nonmitochondrial thermogenesis and improves systemic metabolism through ATF4 activation
Esther Paulo, Yun Zhang, Ruchi Masand…·Biao Wang
The paper identifies NOSEMPE in brown adipocytes as a cause of mitochondrial ETC imbalance and shows it drives nonmitochondrial thermogenesis and metabolic improvement via ATF4 activation.
DOI 10.1101/610220