Author

Evelyn J. Gandy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Andrew S. KennedyiD· 2 shared Brian P. RiesenbergiD· 2 shared Elizabeth G. Hunt· 2 shared Jessica E. ThaxtoniD· 2 shared Katie E. HurstiD· 2 shared Peng Gao· 2 shared Alex M. Andrews· 1 shared Elise L. Sedlacek· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

Andrew S. KennedyORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintNov 16, 2023

Acetyl-CoA Carboxylase Obstructs CD8+ T-Cell Lipid Utilization and Energy Synthesis in the Tumor Microenvironment

Elizabeth G. Hunt, Katie E. Hurst, Andrew S. Kennedy…·Jessica E. Thaxton

This study shows that acetyl-CoA carboxylase (ACC) activity in T cells within the tumor microenvironment inhibits lipid utilization and energy synthesis, and its restriction enhances T cell survival and antitumor function.

DOI 10.1101/2023.11.16.567439

mousehuman

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 16, 2023

Adaptive IRE1 Signaling Elicits T Cell Metabolic Remodeling and Tumor Control

Brian P. Riesenberg, Evelyn J. Gandy, Andrew S. Kennedy…·Jessica E. Thaxton

This study shows that enhancing the adaptive IRE1 UPR pathway in T cells improves tumor control by reducing mitochondrial toxicity and chronic ER stress.

DOI 10.1101/2023.11.16.567431

mousehuman

𝕏 PostBluesky