Petite Integration Factor 1 (PIF1) helicase deficiency increases weight gain in Western diet-fed female mice without increased inflammatory markers or decreased glucose clearance
B. A. Kaufman, F. Belmonte, N. Dedousis, I. Sipula, N. Desai, A. Singhi, y. chu, Y. Zhang, S. Bannwarth, V. Paquis-Flucklinger, L. Harrington, R. M. O'Doherty, M. J. Jurczak
This study shows that PIF1 helicase deficiency in female mice on a Western diet leads to increased weight gain but not inflammation or reduced glucose clearance.
bioRxiv · Aug 16, 2018Physiology