Emergence of Functional Heart-Brain Circuits in a Vertebrate
Luis Hernandez-Nunez, Joana Avrami, S. Shi, Areni Markarian, A. Kim, Jonathan Boulanger-Weill, Virginia M. S. Ruetten, A. Zarghani-Shiraz, Misha B. Ahrens, F. Engert, Mark C. Fishman
This study tracks the development of heart-brain circuits in larval zebrafish, revealing three stages of functional maturation involving vagal motor, sympathetic, and sensory pathways.
bioRxiv · Sep 22, 2025 · PreprintNeuroscience