Author

S. Linderman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Assay:imaging· 1

Frequent Co-Authors

J. Wrammert· 4 shared S. Kumar· 4 shared A. Chandele· 3 shared A. Sharma· 3 shared C. W. Davis· 3 shared E. S. Reddy· 3 shared G. Mantus· 3 shared K. Gottimukkala· 3 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

J. Wrammert

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Author profile →

5 papers

Recent·Most cited

XBB.1.5 monovalent booster improves antibody binding and neutralization against emerging SARS-CoV-2 Omicron variants

S. Jain, S. Kumar, L. Lai, S. Linderman, A. A. Malik, M. L. Ellis, S. Godbole, D. Solis, M. K. Sahoo, K. Bechnak, I. Paredes, R. Tanios, B. Kazzi, S. M. Dib, M. B. Litvack, , M. S. Suthar

The paper evaluates the effectiveness of an XBB.1.5 monovalent booster vaccine, showing improved antibody binding and neutralization against SARS-CoV-2 Omicron variants.

bioRxiv · Feb 3, 2024 · PreprintImmunology

Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response

A. Patel, S. Kumar, L. Lai, C. Chakravarthy, R. Valanparambil, E. S. Reddy, K. Gottimukkala, P. Bajpai, D. R. Raju, V. V. Edara, M. E. Davis-Gardner, S. Linderman, K. Dixit, P. Sharma, G. Mantus, , E. A. Ortlund

The paper identifies three monoclonal antibodies that poorly neutralize the Omicron BA.1 variant, revealing structural and molecular features of antibody evasion.

bioRxiv · Oct 24, 2022Immunology

Structural insights for neutralization of BA.1 and BA.2 Omicron variants by a broadly neutralizing SARS-CoV-2 antibody

S. Kumar, A. Patel, L. Lai, C. Chakravarthy, R. Valanparambil, M. E. Davis-Gardner, V. V. Edara, S. Linderman, E. S. Reddy, K. Gottimukkala, K. Nayak, P. Bajpai, V. Singh, F. Frank, N. Cheedarla, , A. Chandele

This paper identifies and structurally analyzes an antibody that neutralizes SARS-CoV-2 BA.1 and BA.2 variants, revealing its unique epitope and mechanism of action.

bioRxiv · May 13, 2022Immunology

Characterization of neutralizing versus binding antibodies and memory B cells in COVID-19 recovered individuals from India

K. Nayak, K. Gottimukkala, S. Kumar, E. S. Reddy, V. V. Edara, R. Kauffman, K. Floyd, G. Mantus, D. Savargaonkar, P. K. Goel, S. Arora, M. Rahi, C. W. Davis, S. Linderman, J. Wrammert, , A. Chandele

This study examines humoral and memory B cell responses in Indian COVID-19 recovered individuals, finding that RBD-specific IgG correlates with neutralizing antibodies and can serve as a surrogate for neutralization assays.

bioRxiv · Aug 31, 2020Immunology

Probabilistic Models of Larval Zebrafish Behavior: Structure on Many Scales

R. E. Johnson, S. Linderman, T. Panier, C. L. Wee, E. Song, K. J. Herrera, A. Miller, F. Engert

This study models larval zebrafish behavior using probabilistic frameworks to understand how hunger state and environmental factors influence action selection during exploration and hunting.

bioRxiv · Jun 15, 2019Animal Behavior & Cognition