Author

F. Gaiti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2

Frequent Co-Authors

I. M. Ghobrial· 2 shared N. Dusaj· 2 shared O. Abdel-Wahab· 2 shared R. Chaligne· 2 shared A. D. Swett· 1 shared A. G. Hawkins· 1 shared A. S. Nam· 1 shared A. W. Drong· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersCancer Biology

I. M. Ghobrial

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-cell multi-omics defines the cell-type specific impact of splicing aberrations in human hematopoietic clonal outgrowths

F. Gaiti, P. Chamely, A. G. Hawkins, M. Cortes-Lopez, A. D. Swett, S. Ganesan, T. H. Mouhieddine, X. Dai, L. Kluegel, C. Chen, K. Batta, J. Beaulaurier, A. W. Drong, S. Hickey, N. Dusaj, , D. A. Landau

This study introduces GoT-Splice, a multi-omics method to analyze splicing aberrations in human hematopoietic cells, revealing cell-type specific effects of SF3B1 mutations in clonal outgrowths.

bioRxiv · Jun 8, 2022 · PreprintCancer Biology

Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation

A. S. Nam, N. Dusaj, F. Izzo, R. Murali, R. M. Myers, T. Mouhieddine, J. Sotelo, S. Benbarche, M. Waarts, F. Gaiti, S. Tahri, R. Levine, O. Abdel-Wahab, L. A. Godley, R. Chaligne, , D. Landau

This study uses single-cell multi-omics to show DNMT3A R882 mutations cause hypomethylation and alter progenitor cell fates in clonal hematopoiesis.

bioRxiv · Jan 14, 2022 · PreprintCancer Biology

Early origin and deep conservation of enhancers in animals

E. S. Wong, S. Z. Tan, V. Garside, G. Vanwalleghem, F. Gaiti, E. Scott, E. McGlinn, M. Francois, B. M. Degnan

The paper shows enhancer activity is conserved across 700 million years of trans-phyletic divergence.

bioRxiv · May 9, 2019 · PreprintEvolutionary Biology