Author

J. Beaulaurier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

S. Juul· 3 shared A. W. Drong· 2 shared D. J. Turner· 2 shared E. F. DeLong· 2 shared E. Harrington· 2 shared E. Luo· 2 shared J. Eppley· 2 shared S. Hickey· 2 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

S. Juul

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Author profile →

4 papers

Recent·Most cited

De novo antibody discovery in human blood from full-length single B cell transcriptomics and matching haplotyped-resolved germline assemblies

J. Beaulaurier, L. Ly, J. A. Duty, C. Tyer, C. Stevens, C.-t. Hung, A. Sookdeo, A. W. Drong, S. Kowdle, D. J. Turner, S. Juul, S. Hickey, B. Lee

This study uses single-cell transcriptomics and germline haplotype assembly to discover antibodies from human blood post-MMR vaccination, showing neutralization of measles virus.

bioRxiv · Mar 26, 2024 · PreprintImmunology

Single-cell multi-omics defines the cell-type specific impact of splicing aberrations in human hematopoietic clonal outgrowths

F. Gaiti, P. Chamely, A. G. Hawkins, M. Cortes-Lopez, A. D. Swett, S. Ganesan, T. H. Mouhieddine, X. Dai, L. Kluegel, C. Chen, K. Batta, J. Beaulaurier, A. W. Drong, S. Hickey, N. Dusaj, , D. A. Landau

This study introduces GoT-Splice, a multi-omics method to analyze splicing aberrations in human hematopoietic cells, revealing cell-type specific effects of SF3B1 mutations in clonal outgrowths.

bioRxiv · Jun 8, 2022 · PreprintCancer Biology

Novel integrative elements and genomic plasticity in ocean ecosystems

T. Hackl, R. Laurenceau, M. J. Ankenbrand, C. Bliem, Z. Cariani, E. Thomas, K. D. Dooley, A. A. Arellano, S. L. Hogle, P. Berube, G. E. Leventhal, E. Luo, J. Eppley, A. A. Zayed, J. Beaulaurier, , S. W. Chisholm

The paper identifies tycheposons, mobile genetic elements in Prochlorococcus, that drive genomic plasticity through gene exchange and contribute to microbial adaptation in ocean ecosystems.

bioRxiv · Dec 28, 2020Microbiology

Assembly-free single-molecule nanopore sequencing recovers complete virus genomes from natural microbial communities

J. Beaulaurier, E. Luo, J. Eppley, P. Den Uyl, X. Dai, D. J. Turner, M. Pendleton, S. Juul, E. Harrington, E. F. DeLong

This study develops an assembly-free nanopore sequencing method to recover complete virus genomes from environmental samples, revealing new viral structures and genomic features.

bioRxiv · Apr 26, 2019Microbiology