Author

F. Grimm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Asuaje· 1 shared A. Egner· 1 shared A. Gallemi-Perez· 1 shared A. Jain· 1 shared A. Janshoff· 1 shared A. M. Cordes· 1 shared A. Ventura· 1 shared B. R. Brueckner· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

A. Asuaje

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

GOT1 primes the cellular response to hypoxia by supporting glycolysis and HIF1α stabilisation

F. Grimm, A. Asuaje, A. Jain, M. Silva dos Santos, J. Kleinjung, P. M. Nunes, S. Gehrig, L. Fets, J. MacRae, D. Anastasiou

This study identifies GOT1 as a key factor in priming cells for hypoxic adaptation by enhancing glycolysis and HIF1α stabilization before full HIF1 activation.

bioRxiv · Sep 6, 2023 · PreprintCancer Biology

Immortalization and transformation of primary cells mediated by engineered ecDNAs

D. Pradella, M. Zhang, R. Gao, Y. A. Melissa, K. M. Gluchowska, Y. Cendon Florez, T. Mishra, G. La Rocca, M. Weigl, Z. Jiao, H. H. M. Nguyen, F. Grimm, M. Lisi, C. Mastroleo, K. Chen, , A. Ventura

This paper describes a method to engineer large focal amplifications in primary cells using ecDNAs, showing they promote proliferation and transformation.

bioRxiv · Jun 25, 2023 · PreprintCancer Biology

Two-color live-cell STED nanoscopy by click labeling with cell-permeable fluorophores

C. Gregor, F. Grimm, J. Rehman, C. A. Wurm, A. Egner

This paper demonstrates two-color STED nanoscopy using organic fluorophores and click labeling for long-term imaging of living cells.

bioRxiv · Sep 11, 2022Biophysics

Pre-stress of actin cortices is important for the viscoelastic response of living cells

A. M. Cordes, H. Witt, A. Gallemi-Perez, B. R. Brueckner, F. Grimm, M. Vache, T. Oswald, D. Floormann, F. Lautenschlaeger, M. Tarantola, A. Janshoff

This study investigates how pre-stress in actin cortices affects the viscoelastic properties of living cells using a novel model and atomic force microscopy.

bioRxiv · Mar 25, 2020 · PreprintBiophysics