Author

F. Lembo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

J.-P. Borg· 3 shared J.-P. Gorvel· 2 shared S. P. Salcedo· 2 shared T. L. Lacerda· 2 shared A. Beauvois· 1 shared A. Blanco· 1 shared A. Louche· 1 shared A. Volkov· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMicrobiology

J.-P. Borg

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural basis for targeting the human T-cell leukemia virus Tax oncoprotein and syntenin-1 interaction using a small molecule

S. Maseko, I. Van Molle, K. Blibek, C. Gorgulla, J. Olivet, J. Blavier, C. Vandermeulen, S. Skupiewski, D. Saha, T. Ntombela, J. Lim, F. Lembo, A. Beauvois, M. Hamaidia, J.-P. Borg, , J.-C. Twizere

This study identifies the structural basis of Tax-1 interaction with syntenin-1 and demonstrates small-molecule inhibition of this interaction to target HTLV-1.

bioRxiv · Aug 25, 2021 · PreprintBiochemistry

The unique Brucella effectors NyxA and NyxB target SENP3 to modulate the subcellular localisation of nucleolar proteins

A. Louche, A. Blanco, T. L. Lacerda, C. Lionnet, C. Berge, M. Rolando, F. Lembo, J.-P. Borg, C. Buchrieser, M. Nagahama, J.-P. Gorvel, V. Gueguen-Chaignon, L. Terradot, S. P. Salcedo

This study shows that Brucella effectors NyxA and NyxB target SENP3 to alter nucleolar protein localization, promoting bacterial replication.

bioRxiv · Apr 23, 2021 · PreprintMicrobiology

Brucella effector hijacks endoplasmic reticulum quality control machinery to prevent premature egress

J.-B. Luizet, J. Raymond, T. L. Lacerda, M. Bonici, F. Lembo, K. Willemart, J.-P. Borg, J.-P. Gorvel, S. P. Salcedo

This study identifies BspL, a Brucella effector that modulates ERQC to control autophagic vacuole formation and prevent bacterial premature egress.

bioRxiv · Jul 11, 2019 · PreprintMicrobiology